Proteose Intoxications and I N J U R Y of Body Protein. Ii. the Metabolism of Dogs with Duodenal Obstruc- Tion /ind Isolated Loops of Intestine

نویسندگان

  • G. H. WHIPPLE
  • J. V. COOKE
  • T. STEARNS
چکیده

The results which follow the injection of toxic proteoses in normal and immune dogs have been reported in a previous communication. 1 The proteose material was obtained from intestinal obstruction or from closed loops of the intestine. The present paper deals with the reaction which develops in the dog following intestinal obstruction of a certain type or the isolation of closed intestinal loops. I t is clear that the curves of nitrogen elimination show the same high rise above normal following intestinal obstruction as recorded above, as after an injection of a toxic proteose. We have long believed that the intoxication associated with isolated intestinal loops and intestinal obstruction is due to the absorption from the intestinal mucosa of a toxic proteose similar to the proteose which can be isolated from the closed loops or obstructed intestine. These experiments give further support to this belief, and add other facts which are of value for a proper understanding of the various proteose intoxications. Methods.

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تاریخ انتشار 2003